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TSAI, FRANCIS

One or more keywords matched the following items that are connected to TSAI, FRANCIS

Item Type	Name
Academic Article	The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state.
Academic Article	M domains couple the ClpB threading motor with the DnaK chaperone activity.
Academic Article	Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB.
Academic Article	The E3 ubiquitin ligase CHIP binds the androgen receptor in a phosphorylation-dependent manner.
Academic Article	Functional analysis of conserved cis- and trans-elements in the Hsp104 protein disaggregating machine.
Academic Article	Visualizing the ATPase cycle in a protein disaggregating machine: structural basis for substrate binding by ClpB.
Academic Article	The M-domain controls Hsp104 protein remodeling activity in an Hsp70/Hsp40-dependent manner.
Academic Article	CryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation.
Academic Article	Structural basis for intersubunit signaling in a protein disaggregating machine.
Academic Article	Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor.
Concept	Hot Temperature
Concept	Heat-Shock Proteins
Concept	HSP40 Heat-Shock Proteins
Concept	HSP70 Heat-Shock Proteins
Concept	Heat-Shock Response
Concept	HSP90 Heat-Shock Proteins
Academic Article	Crystallization and preliminary X-ray crystallographic analysis of a 40 kDa N-terminal fragment of the yeast prion-remodeling factor Hsp104.
Academic Article	Molecular chaperones in protein quality control.
Academic Article	Crystallization and preliminary X-ray crystallographic analysis of the Hsp100 chaperone ClpB from Thermus thermophilus.
Academic Article	Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.
Academic Article	Structural determinants for protein unfolding and translocation by the Hsp104 protein disaggregase.
Academic Article	Overlapping and Specific Functions of the Hsp104 N Domain Define Its Role in Protein Disaggregation.
Academic Article	Mapping interactions with the chaperone network reveals factors that protect against tau aggregation.
Academic Article	Crystal Structure of the YcjX Stress Protein Reveals a Ras-Like GTP-Binding Protein.
Academic Article	The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis.
Academic Article	Atomic structure of the Leishmania spp. Hsp100 N-domain.
Academic Article	Second Virtual International Symposium on Cellular and Organismal Stress Responses, September 8-9, 2022.
Academic Article	Deciphering the mechanism and function of Hsp100 unfoldases from protein structure.
Academic Article	Structural basis of impaired disaggregase function in the oxidation-sensitive SKD3 mutant causing 3-methylglutaconic aciduria.

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Hot Temperature